- Title
- Spinal cord injuries and nerve dependence in prostate cancer
- Creator
- Rutledge, Alison; Jobling, Phillip; Walker, Marjorie M.; Denham, Jim W.; Hondermarck, Hubert
- Relation
- Trends in Cancer Vol. 3, Issue 12, p. 812-815
- Publisher Link
- http://dx.doi.org/10.1016/j.trecan.2017.10.001
- Publisher
- Cell Press
- Resource Type
- journal article
- Date
- 2017
- Description
- Nerves are emerging as drivers of tumorigenesis, as demonstrated in the mouse where denervation suppresses prostate cancer; however, clinical evidence is needed. Patients with spinal cord injuries (SCIs) resulting in functional denervation of the prostate have a lower incidence of prostate cancer. This may constitute a clinical evidence for nerve dependence in human prostate tumorigenesis.
- Subject
- spinal cord injuries; nerves; prostate cancer; nerve dependence; tumorigenesis
- Identifier
- http://hdl.handle.net/1959.13/1394492
- Identifier
- uon:33706
- Identifier
- ISSN:2405-8033
- Language
- eng
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